“Ending Epidemics: A History of Escape from Contagion” with Richard Conniff

Ending Epidemics on Bridging the Gaps pocast

It is difficult to imagine a not-so-distant past when deadly diseases were a routine part of life. Even more astonishing is the fact that during that time, prevailing medical beliefs attributed these diseases to harmful miasmas, bodily humors, and divine dyspepsia. However, a groundbreaking revelation occurred with the discovery of the world of microorganisms, which led to the understanding that these tiny organisms might be responsible for transmitting and spreading diseases. These pivotal discoveries and understandings paved the way for numerous measures and techniques to prevent the transmission of infectious diseases.

The history of epidemics and humanity’s progress in combating these diseases is full of captivating stories. In his new book, “Ending Epidemics: A History of Escape from Contagion,” prolific author Richard Conniff outlines how our comprehension and prevention of some of the most devastating infectious diseases have advanced, consequently doubling the average life expectancy. In this episode of Bridging the Gaps, I speak with Richard Conniff, delving into moments of inspiration and innovation, decades marked by unwavering determination, and periods of profound suffering that have spurred individuals, institutions, and governments to take action in the pursuit of public health.

Richard Conniff is a prolific author of several non-fiction books and many articles for magazines such as National Geographic, Smithsonian, and Time. He is a contributing opinion writer for the New York Times, and a former commentator on NPR’s “All Things Considered”. He has won the National Magazine Award. He has also written and presented nature programmes for National Geographic television, the Discovery channel and the BBC.

Our conversation begins with an exploration of how communities in old days grappled with epidemics, given their limited understanding of the causes behind such widespread outbreaks. We delve into the intricate ways in which communities tried to comprehend and interpret illnesses before the pivotal discoveries of microorganisms and germs. An engaging segment follows, chronicling the efforts of early pioneers who harnessed the power of microscopes to identify microorganisms believed to be responsible for various diseases.

One captivating narrative we explore revolves around the remarkable utilization of cowpox to foster immunity against smallpox—an extraordinary breakthrough in the history of medicine. However, we also address the resistance encountered by these novel ideas and concepts. We then delve into the emergence of the concept of immunity, the discovery of microorganisms, and the subsequent development of vaccines and antibiotics. Additionally, we discuss the profound realization that improved sanitary conditions are indispensable for safeguarding public health.

Naturally, our conversation turns towards the recent Covid-19 epidemic, examining humanity’s response to this global crisis. Richard offers a significant insight that despite our enhanced capabilities in dealing with epidemics, these formidable diseases persist and may pose future threats if we fail to remain vigilant to the dangers they present.

Complement this discussion with Cloud Empires: Governing State-like Digital Platforms and Regaining Control with Professor Vili Lehdonvirta and then listen to “Kendall Square and the Making of a Global Innovation Hub” with Robert Buderi

By |May 28th, 2023|Biology, Future, History, Podcasts, Research|
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“Worlds Without End: Exoplanets, Habitability, and the Future of Humanity” With Professor Chris Impey

When considering the long-term survival and sustainability of human civilization, two developments hold significant implications. Firstly, humanity has been recklessly depleting resources, causing species extinctions, and degrading essential elements for life on Earth for centuries. Secondly, advancements in the science of discovering habitable planets outside our solar system have opened up the possibility of establishing human civilization beyond our increasingly inhospitable planetary home. In his latest book, “Worlds Without End: Exoplanets, Habitability, and the Future of Humanity,” Professor Chris Impey takes readers on a thrilling journey through the frontiers of astronomy and the search for planets that can potentially support life. In this episode of Bridging the Gaps, I speak with Professor Impey about the science behind finding habitable exoplanets, the evolution of space exploration, and the prospect of humans inhabiting a planet far away from our solar system.

Chris Impey is a University Distinguished Professor of Astronomy at the University of Arizona. He has made significant contributions to the fields of observational cosmology, astrophysics, particularly in the area of exoplanet research. His expertise and passion for the subject have led to many publications and appearances in documentaries, news outlets, and popular science programmes. He has won numerous teaching awards and authored textbooks and many popular science books.

We begin our discussion by examining the historical perspectives on exoplanets, planets beyond our solar system. We then delve into the discovery of the first exoplanet and explore the various methods that scientists have employed to detect these far-off worlds. The Kepler Space Telescope played a pivotal role in this field, and we explore how the James Webb Telescope presents new opportunities for advancing exoplanet research. The diversity of exoplanets is astounding, with variations in size, composition, and orbital characteristics. We delve into these differences and their implications. Additionally, we thoroughly examine the concept of habitability, including how scientists are studying the atmospheric characteristics of these alien worlds. We also touch on the intriguing possibility of orphan planets – large planets without a star – that may sustain habitability characteristics without a sun. We then contemplate the prospect of travelling to these distant planets and potentially establishing human settlements there. We explore the magnitude of such a journey and the challenges involved in interstellar travel. Lastly, we consider the possibility of extraterrestrial life in the universe.

Complement this discussion with Search for Exoplanets: A Discussion with Professor Sara Seager and then listen to “The End of Astronauts”, Robotic Space Exploration and Our Future on Earth and Beyond with Professor Martin Rees”

By |April 16th, 2023|Cosmology, Future, Physics|
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“The Exquisite Machine: The New Science of the Heart” with Professor Sian Harding

The Exquisite Machine on Bridging the Gaps

The heartbeat may be the first physical manifestation of an unborn child that can be seen six weeks after conception, and it continues roughly 100,000 times per day for as long as we are alive. Scientists and researchers have attempted to recreate the heart’s flawless engineering for decades in labs all around the world, but have been unsuccessful. Its exact operation and capacity to meet both our bodily and emotional demands makes it a marvel of engineering that is unmatched by anything built by humans. Any damage to this vital organ of the human body could result in problems that are potentially fatal.

In this episode of Bridging the Gaps I speak with professor Sian Harding about new scientific developments that are opening up the mysteries of the heart, as outlined in her new book “The Exquisite Machine: The New Science of the Heart”. We discuss cutting-edge technologies such as stem cells, gene editing, artificial intelligence and big data that have crucial real-world consequences for health and well-being.These technologies are enabling experiments and clinical trials that will lead to the development of new treatments for heart diseases.

Professor Sian Harding is a leading authority in cardiac science, and emeritus professor of cardiac pharmacology in Imperial College London. She was special advisor to the House of Commons Science and Technology Select Committee on Regenerative Medicine, and has been awarded the Imperial College Medal and a lifetime achievement award from the European Society of Cardiology.

We start off with a detailed discussion of how our present day understanding of the functioning of the human heart developed. We then discuss the cutting edge research on cardiac stem cells, touching upon the experiments where a small number of beating cells were created in the labs. The application of Artificial Intelligence and Big Data Analytics are playing an important role in the field of cardiac research; we go through these topics in detail. Plasticity is a concept that we associate with the brain and its ability to rewire itself to manage any damage or other changes; We discuss the term plastic brain that Sian Harding uses in the book while explaining the resilience of our heart. We then discuss the nervous system that ensures that the heart responds to changing needs. We look into the relation between the emotions and functioning of the heart, discussing that the heart not only responds to our emotions but creates emotions as well. And finally we touch upon the importance of keeping “gender” in mind when developing and implementing solutions for heart related diseases and problems. This has been a highly informative discussion.

Complement this discussion with “Zero to Birth: How the Human Brain Is Built” with Professor William Harris and then listen to “The Next 500 Years: Engineering Life to Reach New Worlds” with Professor Christopher Mason

By |December 1st, 2022|Artificial Intelligence, Biology, Podcasts, Research, Technology|
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