“Spark: The Life of Electricity and the Electricity of Life” with Professor Timothy Jorgensen

Spark Book Review at Bridging the Gaps

When we think about electricity, we most often think of the energy that powers various devices and appliances around us, or perhaps we visualise the lightning-streaked clouds of a stormy sky. But there is more to electricity and “life at its essence is nothing if not electrical”. In this episode of Bridging the Gaps, I speak with Professor Timothy Jorgensen and we discuss his recent book “Spark: The Life of Electricity and the Electricity of Life ”. The book explains the science of electricity through the lenses of biology, medicine and history. It illustrates how our understanding of electricity and the neurological system evolved in parallel, using fascinating stories of scientists and personalities ranging from Benjamin Franklin to Elon Musk. It provides a fascinating look at electricity, how it works, and how it animates our lives from within and without.

We start by discussing the earliest known experiences that humans had with electricity using amber. Amber was most likely the first material with which humans attempted to harness electricity, mostly for medical purposes. Romans used non-static electricity from specific types of fish. Moving on to Benjamin Franklin, we discuss how he attempted to harner the power of electricity and we discuss the earliest forms of devices to store electric charge. We then discuss experiments conducted by Luigi Galvani on dead frogs and by his nephew on dead humans using electricity. As interest in electricity grew, many so-called treatemnts for ailments such as headaches, for bad thoughts and even for sexual difficulties also emerged that were based on the use of electricity; we discuss few interesting examples of such treatments. We then move on to reviewing the cutting edge use of electricity in medical science and discussed medial implants, artificial limbs and deep stimulation technologies and proposed machine-brain interfaces. This has been a fascinating discussion.

Complement this discussion by listening to he Spike: Journey of Electric Signals in Brain from Perception to Action with Professor Mark Humphries and then listen to On Public Communication of Science and Technology with Professor Bruce Lewenstein

By |March 17th, 2022|Artificial Intelligence, Biology, Future, Podcasts, Research|

“The Self-Assembling Brain” and the Quest for Artificial General Intelligence with Professor Peter Robin Hiesinger

How does a network of individual neural cells become a brain? How does a neural network learn, hold information and exhibit intelligence? While neurobiologists study how nature achieves this feat, computer scientists interested in artificial intelligence attempt to achieve it through technology. Are there ideas that researchers in the field of artificial intelligence borrow from their counterparts in the field of neuroscience? Can a better understanding of the development and working of the biological brain lead to the development of improved AI? In his book “The Self-Assembling Brain: How Neural Networks Grow Smarter” professor Peter Robin Hiesinger explores stories of both fields exploring the historical and modern approaches. In this episode of Bridging the Gaps, I speak with professor Peter Robin Hiesinger about the relationship between what we know about the development and working of biological brains and the approaches used to design artificial intelligence systems.

We start our conversation by reviewing the fascinating research that led to the development of neural theory. Professor Hiesigner suggests in the book that to understand what makes a neural network intelligent we must find the answer to the question: is this connectivity or is this learning that makes a neural network intelligent; we look into this argument. We then discuss “the information problem” that how we get information in the brain that makes it intelligent. We also look at the nature vs nurture debate and discuss examples of butterflies that take multigenerational trip, and scout bees that inform the bees in the hive the location and distance of the food. We also discuss the development of the biological brain by GNOME over time. We then shift the focus of discussion to artificial intelligence and explore ideas that the researchers in the field artificial intelligence can borrow from the research in the field of neuroscience. We discuss processes and approaches in the field of computing science such as Cellular Automata, Algorithmic Information Theory and Game of Life and explore their similarities with how GENOME creates the brain over time. This has been an immensely informative discussion.

Complement this discussion by listening to The Spike: Journey of Electric Signals in Brain from Perception to Action with Professor Mark Humphries and then listen to On Task: How Our Brain Gets Things Done” with Professor David Badre.

“Nano Comes to Life”: DNA NanoTech, Medicine and the Future of Biology with Professor Sonia Contera

Nano Comes to Like on Bridging the Gaps

Nanotechnology allows scientists to better understand, interact with, and manipulate biology by creating and manufacturing artificial structures and even machines at the nanoscale out of DNA, proteins, and other biological molecules. From nanoscale machines that can target individual cancer cells and deliver drugs more effectively to nanoantibiotics that can fight resistant bacteria, to the engineering of tissues and organs for research, drug discovery, and transplantation, nanotechnology is revolutionizing medicine in ways that will have profound effects on our health and longevity.

In this episode of Bridging the Gaps I speak with Professor Sonia Contera and we discuss fascinating research that she presents in her book “Nano Comes to Life: How Nanotechnology Is Transforming Medicine and the Future of Biology”. The book introduces readers to nanotechnologies, which are fast advancing and allowing us to influence the basic building components of life. Sonia Contera provides an insider’s view of this new frontier, explaining how nanotechnology permits a new sort of transdisciplinary science that has the potential to give us power over our own biology, health, and lifestyles. Sonia Contera is professor of biological physics in the Department of Physics at the University of Oxford. Her work lies at the interface of physics, biology, and nanotechnology, with a particular focus on the role of mechanics in biology.

We start by discussing the scale at which nanotechnologies function. The evolution of instruments and technology that allow us to perceive and interact with matter on such a microscopic scale is then discussed. The convergence of numerous sciences that are at the heart of such breakthroughs are then discussed, allowing us to build nano-scale structures from the ground up. We then discuss the fascinating research that enables researchers to design proteins on a computer simulator, figure out what kind of GENOME will make such protein from that simulated protein, create that GENOME, and then put it in a real cell to create that protein in reality. We also touch upon the cutting edge research in DNA Nanotechnology and other enabling technologies such as Artificial Intelligence, and the future of biology and medicine. This has been a fascinating discussion.

Complement this discussion by listening to “Artificial Intelligence: Fascinating Opportunities and Emerging Challenges with Professor Bart Selman and then listen to Is Philosophy Dead? On the Bittersweet Relationship Between Science and Philosophy” with Professor Tim Maudlin.